LTPmechanism

In neuroscience, long-term potentiation (LTP) is a persistent strengthening of synapses based on recent patterns of activity. These are patterns of synaptic ...

由 SB Baltaci 著作 · 2019 · 被引用 154 次 — LTP has at least two phases, E-LTP and L-LTP. E-LTP involves modification of existing proteins, independent of gene expression and protein ...

由 Y Hayashi 著作 · 2022 · 被引用 56 次 — Long-term potentiation (LTP) of synaptic transmission is considered to be a cellular counterpart of learning and memory. Activation of postsynaptic NMDA ...

由 L Hao 著作 · 2018 · 被引用 21 次 — LTP is a process whereby brief periods of synaptic activity can produce a long-lasting increase in synapse strength. There are three properties ...

由 T Sumi 著作 · 2020 · 被引用 77 次 — NMDA-receptor dependent LTP is thought to occur by incorporating AMPARs into the synaptic membrane through either the exocytosis of the ...

由 WC Abraham 著作 · 2019 · 被引用 267 次 — LTP and LTD. LTP is the most studied form of synaptic plasticity, and the one that, in mammals, is most closely linked to memory storage.

The most popular school of thought is that LTP arises from changes in the sensitivity of the postsynaptic cell to glutamate, either by rapid addition of new ...

One way to induce LTP is to use high-frequency stimulation to release large amounts of neurotransmitter to depolarize the postsynaptic cell. Different ...